POU2AF1 抗体 (AA 1-100)
Quick Overview for POU2AF1 抗体 (AA 1-100) (ABIN1714116)
抗原
See all POU2AF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BOB1
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亚型
- IgG
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anti-POU Class 2 Associating Factor 1 (POU2AF1) (AA 148-255) antibody
POU2AF1 适用: 人 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal BOB1-2424 unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (AA 148-255) antibodyPOU2AF1 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal BOB1-2421 unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) antibodyPOU2AF1 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 4A5 unconjugated Recombinant Antibody
anti-POU Class 2 Associating Factor 1 (POU2AF1) (C-Term) antibodyVerified POU2AF1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (AA 1-27), (N-Term) antibodyPOU2AF1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22378 unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) antibodyPOU2AF1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (C-Term) antibodyVerified POU2AF1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (C-Term) antibodyPOU2AF1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) (AA 7-36), (N-Term) antibodyPOU2AF1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-POU Class 2 Associating Factor 1 (POU2AF1) antibodyPOU2AF1 适用: 人 WB 宿主: 小鼠 Monoclonal 7C1 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))
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别名
- BOB1
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背景
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Synonyms: B cell Oct binding protein 1, B cell specic coactivator OBF 1, B cell specic coactivator OBF1, B-cell-specic coactivator OBF-1, BOB 1, BOB-1, OBF 1, OBF1, OBF1_HUMAN, OCA B, OCA-B, OCAB, OCT binding factor 1, OCT-binding factor 1, POU domain class 2 associating factor 1, POU domain class 2-associating factor 1, POU2AF1.
Background: POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA. The versatility of POU protein operation is additionally conferred at the dimerization level. The POU dimer from the OCT1 gene formed on the palindromic OCT factor recognition element, or PORE (ATTTGAAATGCAAAT), could recruit the transcriptional coactivator OBF1. Studies of tissue-specific expression of immunoglobulin promoters demonstrate the importance of an octamer, ATTTGCAT, and the proteins that bind to it. This is a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. Oct-1 encodes one protein, NF-A1, which is found in nuclear extracts from all cell types and thus is not specific to lymphoid cells as is the protein NF-A2, which is encoded by Oct-2. A novel protein designated Bob 1 (B cell Oct binding protein 1), alternatively called OBF-1, specifically interacts with Oct-1 and Oct-2, enhancing their transcriptional efficacy. Bob 1 is expressed at highest levels in spleen and peripheral blood leukocytes and represents an Oct co-factor capable of conferring cell-specific activation of Oct-1 and Oct-2. Although having no intrinsic capacity for DNA binding, Bob 1 associates tightly with the octamer motif in the presence of Oct-1 and/or Oct-2. The gene which encodes Bob 1 maps to human chromosome 11q23.1.
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基因ID
- 5450
抗原
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