BNIP3 抗体 (pSer95)
Quick Overview for BNIP3 抗体 (pSer95) (ABIN1713649)
抗原
See all BNIP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer95
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交叉反应
- 人
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预测反应
- Dog,Cow,Sheep,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human BNIP3 around the phosphorylation site of Ser95
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亚型
- IgG
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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 50-155) antibody
BNIP3 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6A5F7 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 1-164) antibodyBNIP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 50-155) antibodyBNIP3 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E11F4 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 152-187) antibodyBNIP3 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 3-134) antibodyBNIP3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 1-164) antibodyBNIP3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 112-124) antibodyBNIP3 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 215-252) antibodyBNIP3 适用: 人, 小鼠 IF, IHC (p) 宿主: 兔 Polyclonal RB3385 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (BH3 Domain) antibodyBNIP3 适用: 人, 小鼠 WB, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 152-187) antibodyBNIP3 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
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别名
- BNIP3
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背景
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Synonyms: BNIP3 phospho S95, p-BNIP3 phospho S95, BCL2 Adenovirus E1B 19 kDa Interacting Protein 3, BCL2/adenovirus E1B 19 kDa protein interacting protein 3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BNIP 3, BNIP3, BNIP3_HUMAN, NIP 3, NIP3.
Background: The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.
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基因ID
- 664
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途径
- Autophagy, Brown Fat Cell Differentiation
抗原
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