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FZD8 抗体 (PE-Cy5.5)

This anti-FZD8 antibody is a 兔 多克隆 antibody detecting FZD8 in WB. Suitable for 人, 小鼠, 大鼠 和 Cow.
产品编号 ABIN1713129
发货至: 中国

Quick Overview for FZD8 抗体 (PE-Cy5.5) (ABIN1713129)

抗原

See all FZD8 抗体
FZD8 (Frizzled Family Receptor 8 (FZD8))

适用

  • 60
  • 47
  • 35
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow

宿主

  • 58
  • 3
  • 2
  • 1

克隆类型

  • 54
  • 10
多克隆

标记

  • 31
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FZD8 antibody is conjugated to PE-Cy5.5

应用范围

  • 40
  • 19
  • 15
  • 11
  • 11
  • 6
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Frizzled 8

    亚型

    IgG
  • 应用备注

    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FZD8 (Frizzled Family Receptor 8 (FZD8))

    别名

    Frizzled 8

    背景

    Synonyms: Frizzled 8 seven transmembrane spanning receptor, frizzled 8, seven transmembrane spanning receptor, Frizzled family receptor 8, frizzled homolog 8 Drosophila, Frizzled homolog 8, Frizzled-8, FZ 8, Fz-8, FZ8, FZD 8, FZD8, FZD8_HUMAN, hFZ 8, hFZ8, HGNC4046, Homolog of Drosophila Frizzled 8.

    Background: The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins (FRPs), have been described. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy-terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt and are generally coupled to G proteins. The cysteine-rich domain of frizzled-8 blocks endogenous Wnts and the effects of Wnt-1 and Wnt-5 on proliferation. The mouse frizzled-8 gene, which encodes a Wnt receptor, is a potent cancer-associated activator of the Beta-catenin-TCF pathway. The frizzled-8 gene contains no introns. Frizzled-8 mRNA has been detected in fetal brain and kidney, and also in adult pancreas, skeletal muscle, kidney and heart. Frizzled is highly expressed in HeLa S3 (cervical uterus cancer) cells and A549 lung cancer cells.

    基因ID

    8325

    途径

    WNT signaling
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