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p130 抗体 (AA 51-150) (HRP)

This anti-p130 antibody is a 兔 多克隆 antibody detecting p130 in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1712085
发货至: 中国

Quick Overview for p130 抗体 (AA 51-150) (HRP) (ABIN1712085)

抗原

See all p130 (RBL2) 抗体
p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

适用

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宿主

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克隆类型

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多克隆

标记

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This p130 antibody is conjugated to HRP

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 51-150

    预测反应

    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Rb2 p130

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))

    别名

    Rb2 p130

    背景

    Synonyms: 130 kDa retinoblastoma associated protein, FLJ26459, p130, PRB 2, PRB2, Rb 2, Rb2, RBL2, RBR 2, RBR2, Retinoblastoma like 2, Retinoblastoma like protein 2, Retinoblastoma Related Gene.

    Background: p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and is known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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