FERMT2 抗体 (AA 352-420) (Cy5.5)
Quick Overview for FERMT2 抗体 (AA 352-420) (Cy5.5) (ABIN1706289)
抗原
See all FERMT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 352-420
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Kindlin 2/MIG2
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FERMT2 (Fermitin Family Member 2 (FERMT2))
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别名
- Kindlin 2/MIG2
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背景
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Synonyms: FLJ34213, FLJ44462, UNC112, FERM2_HUMAN, Fermitin family homolog 2, Fermt2, KIND2, Kindlin-2, MIG-2, MIG2, Mitogen-inducible gene 2 protein, PH domain-containing family C member 1, Pleckstrin homology domain containing family C with FERM domain member 1, Pleckstrin homology domain-containing family C member 1, PLEKHC1, UNC112B.
Background: Mig-2 recruits migfilin to cell-matrix adhesions, while the interaction with filamin mediates the association of migfilin with actin filaments. Together, Mig-2, migfilin and filamin define a connection between cell matrix adhesions and the actin cytoskeleton and participate in the orchestration of actin assembly and cell shape modulation. Mig-2 expression is transcriptionally elevated in leiomyomas and could be involved in its hormone-mediated growth of leiomyomas of the uterus. Expression of Mig-2 is ubiquitous, and it is found in numerous tumor tissues.
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基因ID
- 10979
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途径
- Cell-Cell Junction Organization
抗原
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