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FERMT2 抗体 (AA 380-550)

FERMT2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6140582
发货至: 中国
  • 抗原 See all FERMT2 抗体
    FERMT2 (Fermitin Family Member 2 (FERMT2))
    抗原表位
    • 15
    • 14
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 380-550
    适用
    • 48
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 40
    • 8
    克隆类型
    • 40
    • 8
    多克隆
    标记
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FERMT2 antibody is un-conjugated
    应用范围
    • 43
    • 23
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    KVFKPKKLTL KGYKQYWCTF KDTSISCYKS KEESSGTPAH QMNLRGCEVT PDVNISGQKF NIKLLIPVAE GMNEIWLRCD NEKQYAHWMA ACRLASKGKT MADSSYNLEV QNILSFLKMQ HLNPDPQLIP EQITTDITPE CLVSPRYLKK YKNKQITARI LEAHQNVAQM S
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 380-550 of human FERMT2 (NP_006823.1).
    亚型
    IgG
    Top Product
    Discover our top product FERMT2 Primary Antibody
  • 应用备注
    WB,1:1000 - 1:2000,IHC,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    FERMT2 (Fermitin Family Member 2 (FERMT2))
    别名
    FERMT2 (FERMT2 产品)
    别名
    AA960555 antibody, Kindlin-2 antibody, Mig2 antibody, Plekhc1 antibody, KIND2 antibody, MIG2 antibody, PLEKHC1 antibody, UNC112 antibody, UNC112B antibody, mig-2 antibody, fermitin family member 2 antibody, Fermt2 antibody, FERMT2 antibody
    背景
    Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.,FERMT2,KIND2,MIG2,PLEKHC1,UNC112,UNC112B,mig-2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Stem Cells,Mesenchymal Stem Cells,FERMT2
    分子量
    72 kDa/77 kDa/78 kDa
    基因ID
    10979
    UniProt
    Q96AC1
    途径
    Cell-Cell Junction Organization
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