我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

ERBB3 抗体 (pTyr1276) (Cy5.5)

Name: ERBB3 抗体 (pTyr1276) (Cy5.5)
SKU: ABIN1705585
Availability: OutOfStock

This anti-ERBB3 antibody is a 兔多克隆 antibody detecting ERBB3 in IF (p) 和 IF (cc). Suitable for 大鼠和犬.

产品编号 ABIN1705585

发货至: 中国

Quick Overview for ERBB3 抗体 (pTyr1276) (Cy5.5) (ABIN1705585)

抗原

See all ERBB3 抗体

ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

适用

大鼠, 犬

宿主

兔

克隆类型

多克隆

标记

This ERBB3 antibody is conjugated to Cy5.5

应用范围

Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Discover our top product ERBB3 Primary Antibody

抗原表位
27

26

15

14

14

9

8

7

6

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr1276

交叉反应

犬, 大鼠

预测反应

Human,Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human HER3 around the phosphorylation site of Tyr1276

亚型

IgG
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 707-964) antibody
ERBB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55), (N-Term) antibody
ERBB3 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01467 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibody
ERBB3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-130) antibody
ERBB3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibody
ERBB3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55) antibody
ERBB3 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1328) antibody
ERBB3 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 661-760) antibody
ERBB3 适用: 人, 小鼠, 大鼠 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 21-332) antibody
ERBB3 适用: 人 IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F12 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-131) antibody
ERBB3 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated

应用备注

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

别名

HER3

背景

Synonyms: Her3/ErbB3Tyr1276, p-HRE3 Tyr1276, ErbB 3 phospho Y1276, ERBB3, c erbB 3, c erbB3, ERBB3 protein, erbB3 S, Glial growth factor receptor, HER 3, HER3, LCCS2, MDA BF 1, MGC88033, p180 ErbB3, p45 sErbB3, p85 sErbB3, proto-oncogene-like protein c ErbB 3, proto-oncogene-like protein c ErbB3, receptor tyrosine protein kinase ERB3, Receptor tyrosine protein kinase erbB 3, Receptor tyrosine protein kinase erbB3, Tyrosine kinase type cell surface receptor HER3, ERBB3_HUMAN.
Background: ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. Isoform 2 lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized. Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2), also called Israeli Bedouin multiple contracture syndrome type A. LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord.

基因ID

2065

途径

RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway