HHAT 抗体 (AA 101-200) (Cy5.5)
Quick Overview for HHAT 抗体 (AA 101-200) (Cy5.5) (ABIN1705467)
抗原
See all HHAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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预测反应
- Human,Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HHAT
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HHAT (Hedgehog Acyltransferase (HHAT))
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别名
- Hhat
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背景
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Synonyms: 2810432O22Rik, AC115917.1, AI462858, FLJ10724, FLJ34867, Hedgehog acyltransferase, Hhat, HHAT_HUMAN, MART 2, MART-2, MART2, Melanoma antigen recognized by T cells 2, Melanoma antigen recognized by T-cells 2, MGC11697, OTTMUSP00000033669, Protein cysteine N palmitoyltransferase HHAT, Protein-cysteine N-palmitoyltransferase HHAT, RGD1311746, SKI1, Skinny hedgehog protein 1, Skinny hedgehog protein, Skn.
Background: HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8 % of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.
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基因ID
- 55733
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途径
- Hedgehog Signaling
抗原
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