CRTC3 抗体 (AA 151-260) (Cy5)
Quick Overview for CRTC3 抗体 (AA 151-260) (Cy5) (ABIN1704473)
抗原
See all CRTC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-260
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CRTC3/TORC3
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
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别名
- CRTC3/TORC3
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背景
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Synonyms: CREB regulated transcription coactivator 3, CREB-regulated transcription coactivator 3, CRTC 3, CRTC3, CRTC3_HUMAN, FLJ21868, TORC 3, TORC-3, TORC3, Transducer of CREB protein 3, Transducer of regulated cAMP response element binding protein CREB 3, Transducer of regulated cAMP response element binding protein 3, Transducer of regulated cAMP response element-binding protein 3, Transducer of regulated CREB protein 3.
Background: TORC3 is a 619 amino acid protein that localizes to both the cytoplasm and the nucleus and belongs to the TORC family. Expressed in lung tissue and B and T lymphocytes, as well as in colon, brain, ovary, kidney, prostate, colon and heart, TORC3 functions as a transcriptional coactivator for CREB-1, thereby regulating the expression of CREB-activated genes, and is also thought to activate the SIK/TORC signaling pathway. TORC3 exists as multiple alternatively spliced isoforms and, in addition to its role in transcriptional activation, is thought to induce mitochondrial biogenesis, specifically in muscle cells.
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基因ID
- 64784
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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