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FANCD2 抗体 (pSer1404) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-FANCD2 antibody specifically detects FANCD2 in ELISA, IHC (p) 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN1701579
发货至: 中国
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北京 101111
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Quick Overview for FANCD2 抗体 (pSer1404) (Biotin) (ABIN1701579)

抗原

See all FANCD2 抗体
FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

适用

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宿主

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克隆类型

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多克隆

标记

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This FANCD2 antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer1404

    交叉反应

    预测反应

    Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser1404

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

    别名

    FANCD2

    背景

    Synonyms: FANCD2 phospho S1404, FANCD2 phospho Ser1404, p-FANCD2 phospho S1404, FA 4, FA D2, FA4, FAC D2, FACD 2, FACD, FACD2, FAD, FAD2, FANC D2, FANCD 2, FANCD, Protein FACD2, Type 4 Fanconi pancytopenia, FACD2_HUMAN, Fanconi anemia group D2 protein, Protein FACD2.

    Background: Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.

    基因ID

    2177

    途径

    DNA Damage Repair
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