FANCD2 抗体 (pSer1404) (Biotin)
Quick Overview for FANCD2 抗体 (pSer1404) (Biotin) (ABIN1701579)
抗原
See all FANCD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1404
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交叉反应
- 人
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预测反应
- Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser1404
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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别名
- FANCD2
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背景
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Synonyms: FANCD2 phospho S1404, FANCD2 phospho Ser1404, p-FANCD2 phospho S1404, FA 4, FA D2, FA4, FAC D2, FACD 2, FACD, FACD2, FAD, FAD2, FANC D2, FANCD 2, FANCD, Protein FACD2, Type 4 Fanconi pancytopenia, FACD2_HUMAN, Fanconi anemia group D2 protein, Protein FACD2.
Background: Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
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基因ID
- 2177
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途径
- DNA Damage Repair
抗原
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