FANCA 抗体 (AA 461-560) (Biotin)
Quick Overview for FANCA 抗体 (AA 461-560) (Biotin) (ABIN1700471)
抗原
See all FANCA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 461-560
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FANCA
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亚型
- IgG
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anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibody
FANCA 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-297) antibodyFANCA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1121-1170), (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 995-1009) antibodyFANCA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 609-813) antibodyFANCA 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibodyFANCA 适用: 人 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 71-120) antibodyFANCA 适用: 人, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-275) antibodyFANCA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) antibodyFANCA 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- FANCA (Fanconi Anemia Group A Protein (FANCA))
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别名
- FANCA
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背景
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Synonyms: FA 1, FA, FA H, FA1, FAA, FACA, FAH, Fanca, FANCA_HUMAN, FANCH, Fanconi anemia complementation group A, Fanconi anemia complementation group H, Fanconi anemia group A protein, Fanconi anemia type 1, MGC75158, Protein FACA.
Background: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. At least eight complementation groups (A-G) have been identified and six FA genes (for subtypes A, C, D2, E, F and G) have been cloned. The FA proteins lack sequence homologies or motifs that could point to a molecular function. The cellular accumulation of FA proteins, including FANCA and FANCG, is subject to regulation by TNF alpha signaling. Phosphorylation of FANC (Fanconi anemia complementation group) proteins is thought to be important for the function of the FA pathway. FANCA, also known as FACA and FANCH, associates with the Brm-related gene 1 (BRG1) product, a subunit of the SWI/SNF complex which remodels chromatin structure through a DNA-dependent ATPase activity. FANCA is mainly expressed in lymphoid tissues, testis and ovary. The amino-terminal region of the FANCA protein is required for FANCG binding, FANCC binding, nuclear localization and functional activity of the complex. The human FANCA gene maps to chromosome 16q24.3 and encodes a 1,455 amino acid protein.
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基因ID
- 2175
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途径
- DNA Damage Repair
抗原
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