FLT1 抗体 (AA 1100-1200)
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北京 101111
Quick Overview for FLT1 抗体 (AA 1100-1200) (ABIN1683256)
抗原
See all FLT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1100-1200
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序列
- YPGVQMDEDF CSRLREGMRM RAPEYSTPEI YQIMLDCWHR DPKERPRFAE LVEKLGDLLQ ANVQQDGKDY IPINAILTGN SGFTYSTPAF SEDFFKESIS A
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1100-1200 of human VEGFR1 (NP_002010.2).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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别名
- FLT1
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背景
- This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.,FLT,FLT-1,VEGFR-1,VEGFR1,FLT1,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,VEGF,VEGF Receptors,Endocrine & Metabolism,Cardiovascular,Angiogenesis,Angiogenic growth factors,Hypoxia,FLT1
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分子量
- 39 kDa/41 kDa/52- 82 kDa/150 kDa
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基因ID
- 2321
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UniProt
- P17948
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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