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Nibrin 抗体 (AA 435-754)

Name: Nibrin 抗体 (AA 435-754)
Brand: antibodies-online
SKU: ABIN1681204
Availability: OutOfStock

This anti-Nibrin antibody is a 兔多克隆 antibody detecting Nibrin in WB 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis of extracts of various cell lines, using NBS1/NBS1/NBN antibody (ABIN1681204, ABIN3015326, ABIN3015327 and ABIN5663771) at 1:1000 dilution. (Nibrin 抗体 (AA 435-754))

Western blot analysis of extracts of various cell lines, using NBN antibody. (Nibrin 抗体 (AA 435-754))

Western blot analysis of extracts from normal (control) and NBS1/NBS1/NBN knockout (KO) 293T cells, using NBS1/NBS1/NBN antibody (ABIN1681204, ABIN3015326, ABIN3015327 and ABIN5663771) at 1:1000 dilution. (Nibrin 抗体 (AA 435-754))

Immunohistochemistry of paraffin-embedded human lung cancer using [KO Validated] NBS1/NBS1/NBN Rabbit pAb (ABIN1681204, ABIN3015326, ABIN3015327 and ABIN5663771) at dilution of 1:50 (40x lens). (Nibrin 抗体 (AA 435-754))

IHC

4 images

(2 references)

产品编号 ABIN1681204

发货至: 中国

Quick Overview for Nibrin 抗体 (AA 435-754) (ABIN1681204)

抗原

See all Nibrin (NBN) 抗体

Nibrin (NBN)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Nibrin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product NBN Primary Antibody

抗原表位
39

15

10

8

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

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1

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1

1

1

1

1
AA 435-754

序列

KLPSINKSKD RASQQQQTNS IRNYFQPSTK KRERDEENQE MSSCKSARIE TSCSLLEQTQ PATPSLWKNK EQHLSENEPV DTNSDNNLFT DTDLKSIVKN SASKSHAAEK LRSNKKREMD DVAIEDEVLE QLFKDTKPEL EIDVKVQKQE EDVNVRKRPR MDIETNDTFS DEAVPESSKI SQENEIGKKR ELKEDSLWSA KEISNNDKLQ DDSEMLPKKL LLTEFRSLVI KNSTSRNPSG INDDYGQLKN FKKFKKVTYP GAGKLPHIIG GSDLIAHHAR KNTELEEWLR QEMEVQNQHA KEESLADDLF RYNPYLKRRR

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 435-754 of human NBS1/NBS1/NBN (NP_002476.2).

亚型

IgG
anti-Nibrin (NBN) (AA 467-615) antibody
NBN 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7E4C2 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E7 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6E11 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated

anti-Nibrin (NBN) (AA 645-754) antibody
NBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 714-745), (C-Term) antibody
NBN 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (pSer343) antibody
NBN 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:1000,IHC,1:50 - 1:100

限制

仅限研究用
缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
抗原

Nibrin (NBN)

别名

NBN

背景

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.,NBN,AT-V1,AT-V2,ATV,NBS,NBS1,P95,nibrin,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,NBN

分子量

84 kDa

基因ID

4683

UniProt

O60934

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response