DDB1 抗体 (C-Term)
Quick Overview for DDB1 抗体 (C-Term) (ABIN1679509)
抗原
See all DDB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LGEFVNVFCH GSLVMQNLGE TSTPTQGSVL FGTVNGMIGL VTSLSESWYN LLLDMQNRLN KVIKSVGKIE HSFWRSFHTE RKTEPATGFI DGDLIESFLD ISRPKMQEVV ANLQYDDGSG MKREATADDL IKVVEELTRI H
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1000 to the C-terminus of human DDB1 (NP_001914.3).
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亚型
- IgG
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anti-Damage Specific DNA Binding Protein 1 (DDB1) (C-Term) antibody
Verified DDB1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (C-Term) antibodyKO Validated DDB1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) antibodyDDB1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) antibodyDDB1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (AA 1011-1140) antibodyDDB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (AA 1011-1140) antibodyDDB1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (AA 1044-1140) antibodyDDB1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) antibodyDDB1 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (C-Term) antibodyDDB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Damage Specific DNA Binding Protein 1 (DDB1) (AA 741-943) antibodyDDB1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))
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别名
- DDB1
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背景
- The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins.,DDB1,DDBA,UV-DDB1,XAP1,XPCE,XPE,XPE-BF,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Endocrine & Metabolism,Carbohydrate metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,DDB1
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分子量
- 50 kDa/126 kDa
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基因ID
- 1642
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UniProt
- Q16531
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途径
- DNA Damage Repair
抗原
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