Cyclin B2 抗体 (AA 1-100)
Quick Overview for Cyclin B2 抗体 (AA 1-100) (ABIN1679041)
抗原
See all Cyclin B2 (CCNB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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序列
- MALLRRPTVS SDLENIDTGV NSKVKSHVTI RRTVLEEIGN RVTTRAAQVA KKAQNTKVPV QPTKTTNVNK QLKPTASVKP VQMEKLAPKG PSPTPEDVSM
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Cyclin B2 (NP_004692.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway." in: Redox biology, Vol. 14, pp. 338-353, (2018) (PubMed).
: "Upregulation of Cdh1 Attenuates Isoflurane-Induced Neuronal Apoptosis and Long-Term Cognitive Impairments in Developing Rats." in: Frontiers in cellular neuroscience, Vol. 11, pp. 368, (2017) (PubMed).
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: "Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway." in: Redox biology, Vol. 14, pp. 338-353, (2018) (PubMed).
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- Cyclin B2 (CCNB2)
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别名
- CCNB2
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背景
- Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.,CCNB2,HsT17299,cyclin B2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,G2/M DNA Damage Checkpoint,CCNB2
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分子量
- 45 kDa
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基因ID
- 9133
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UniProt
- O95067
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途径
- Cell Division Cycle, M Phase
抗原
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