CASR 抗体 (AA 874-1088)
(1 reference)Quick Overview for CASR 抗体 (AA 874-1088) (ABIN1678994)
抗原
See all CASR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 874-1088
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序列
- PSRNTIEEVR CSTAAHAFKV AARATLRRSN VSRKRSSSLG GSTGSTPSSS ISSKSNSEDP FPQPERQKQQ QPLALTQQEQ QQQPLTLPQQ QRSQQQPRCK QKVIFGSGTV TFSLSFDEPQ KNAMAHRNST HQNSLEAQKS SDTLTRHQPL LPLQCGETDL DLTVQETGLQ GPVGGDQRPE VEDPEELSPA LVVSSSQSFV ISGGGSTVTE NVVNS
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 874-1088 of human CASR (NP_001171536.1).
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亚型
- IgG
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anti-Calcium-Sensing Receptor (CASR) (pThr888) antibody
CASR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 121-220) antibodyCASR 适用: Pig WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (C-Term) antibodyCASR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) antibodyCASR 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 926-1078) antibodyCASR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 216-229), (Extracellular) antibodyCASR 适用: 人 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 863-1079) antibodyCASR 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) antibodyCASR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 260-287) antibodyCASR 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41198 unconjugated
anti-Calcium-Sensing Receptor (CASR) (N-Term) antibodyCASR 适用: 人, 小鼠, 大鼠, Pig, Cow, 猴, 兔, Bat, 小鸡, 犬, Hamster, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor." in: Journal of the American Heart Association, Vol. 6, Issue 4, (2017) (PubMed).
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: "Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor." in: Journal of the American Heart Association, Vol. 6, Issue 4, (2017) (PubMed).
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- CASR (Calcium-Sensing Receptor (CASR))
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别名
- CASR
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背景
- The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.,CASR,CAR,EIG8,FHH,FIH,GPRC2A,HHC,HHC1,HYPOC1,NSHPT,PCAR1,hCasR,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,Endocrine & Metabolism,Neuroscience,Calcium Signaling,CASR
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分子量
- 120 kDa/121 kDa
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基因ID
- 846
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UniProt
- P41180
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途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
抗原
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