APC 抗体 (AA 2544-2843)
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北京 101111
Quick Overview for APC 抗体 (AA 2544-2843) (ABIN1678690)
抗原
See all APC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2544-2843
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序列
- SGTWKREHSK HSSSLPRVST WRRTGSSSSI LSASSESSEK AKSEDEKHVN SISGTKQSKE NQVSAKGTWR KIKENEFSPT NSTSQTVSSG ATNGAESKTL IYQMAPAVSK TEDVWVRIED CPINNPRSGR SPTGNTPPVI DSVSEKANPN IKDSKDNQAK QNVGNGSVPM RTVGLENRLN SFIQVDAPDQ KGTEIKPGQN NPVPVSETNE SSIVERTPFS SSSSSKHSSP SGTVAARVTP FNYNPSPRKS SADSTSARPS QIPTPVNNNT KKRDSKTDST ESSGTQSPKR HSGSYLVTSV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 2544-2843 of human APC (NP_000029.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- APC (Adenomatous Polyposis Coli (APC))
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别名
- APC
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背景
- This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.,APC,BTPS2,DP2,DP2.5,DP3,GS,PPP1R46,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cell Adhesion,Microtubules,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Cell Type Marker,Stem Cells,Cardiovascular,Heart,Cardiogenesis,Oligodendrocyte marker,APC
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分子量
- 300 kDa/311 kDa
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基因ID
- 324
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UniProt
- P25054
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途径
- WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
抗原
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