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APC 抗体 (AA 2544-2843)

This anti-APC antibody is a 兔 多克隆 antibody detecting APC in WB 和 IHC. Suitable for 人.
产品编号 ABIN1678690
发货至: 中国

Quick Overview for APC 抗体 (AA 2544-2843) (ABIN1678690)

抗原

See all APC 抗体
APC (Adenomatous Polyposis Coli (APC))

适用

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宿主

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克隆类型

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多克隆

标记

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This APC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 2544-2843

    序列

    SGTWKREHSK HSSSLPRVST WRRTGSSSSI LSASSESSEK AKSEDEKHVN SISGTKQSKE NQVSAKGTWR KIKENEFSPT NSTSQTVSSG ATNGAESKTL IYQMAPAVSK TEDVWVRIED CPINNPRSGR SPTGNTPPVI DSVSEKANPN IKDSKDNQAK QNVGNGSVPM RTVGLENRLN SFIQVDAPDQ KGTEIKPGQN NPVPVSETNE SSIVERTPFS SSSSSKHSSP SGTVAARVTP FNYNPSPRKS SADSTSARPS QIPTPVNNNT KKRDSKTDST ESSGTQSPKR HSGSYLVTSV

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 2544-2843 of human APC (NP_000029.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    APC (Adenomatous Polyposis Coli (APC))

    别名

    APC

    背景

    This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.,APC,BTPS2,DP2,DP2.5,DP3,GS,PPP1R46,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cell Adhesion,Microtubules,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Cell Type Marker,Stem Cells,Cardiovascular,Heart,Cardiogenesis,Oligodendrocyte marker,APC

    分子量

    300 kDa/311 kDa

    基因ID

    324

    UniProt

    P25054

    途径

    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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