SETD7 抗体 (AA 1-366)
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Quick Overview for SETD7 抗体 (AA 1-366) (ABIN165458)
抗原
See all SETD7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-366
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原理
- Human SETD7 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human SET 7/9 (1-366aa) purified from E. coli
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亚型
- IgG2b kappa
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应用备注
- Recommended dilution 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
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别名
- SETD7
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背景
- SET 7/9 is a histone methyltransferase (HMTase) that transfers methyl group to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. Set7/9, unlike most other SET proteins, is exclusively a mono-methylase.
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NCBI登录号
- NP_085151
抗原
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