HSP27 抗体 (AA 1-205)
Quick Overview for HSP27 抗体 (AA 1-205) (ABIN165408)
抗原
See all HSP27 (HSPB1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-205
-
纯化方法
- The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
-
免疫原
- Recombinant human Hsp27 (1-205aa) purified from E. coli
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
- Recommended dilution 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
-
- HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
-
别名
- HSP27
-
背景
- Hsp27 (also known as the Estrogen-Regulated 24k protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPkAP kinase 2 and the stress-activated protein kinase SAPk2 (p38). Hsp27 forms a multimeric complex within cells, and its primary chaperone function, like other small Hsps, appears to be the stabilization of denatured or aggregated proteins in a refolding competent state.
-
NCBI登录号
- NP_001531
-
途径
- MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
抗原
-