Chromosomal location: 5 C3.3, 5 42.0 cM Produced from sera of rabbits immunised with a peptide of the C-terminal end of native mouse soluble VEGFR-2/Flk-1 (GMEASLGDRIAMP).
纯化方法
Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A.
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
缓冲液
PBS
注意事项
Centrifuge vial prior to opening.
储存条件
4 °C,-20 °C
储存方法
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
有效期
24 months
抗原
VEGFR2/CD309 (VEGFR2)
(VEGF Receptor 2 (VEGFR2))
别名
VEGFR-2/Flk-1
背景
Soluble vascular endothelial growth factor receptor-2 , soluble Kdr, soluble Ly73, soluble Flk-1, sVEGFR2, sVEGF receptor 2, soluble kinase insert domain protein receptor,The antibody recognizes solely the endogenous soluble form of mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. The endogenous soluble mouse esFlk-1 generated by alternative splicing consists of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle, other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C, ligand binding plays a key role in vascular development and vascular permeability.