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VEGFR2/CD309 抗体 (Soluble)

This anti-VEGFR2/CD309 antibody is a 兔 多克隆 antibody detecting VEGFR2/CD309 in WB. Suitable for 小鼠.
产品编号 ABIN1589863
发货至: 中国

Quick Overview for VEGFR2/CD309 抗体 (Soluble) (ABIN1589863)

抗原

See all VEGFR2/CD309 (VEGFR2) 抗体
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This VEGFR2/CD309 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Soluble

    原理

    VEGFR-2/Flk-1 (Peptide), soluble antibody

    特异性

    Peptide: GMEASLGDRIAMP

    产品特性

    Chromosomal location: 5 C3.3, 5 42.0 cM
    Produced from sera of rabbits immunised with a peptide of the C-terminal end of native mouse soluble VEGFR-2/Flk-1 (GMEASLGDRIAMP).

    纯化方法

    Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A.

    免疫原

    Peptide: GMEASLGDRIAMP

    亚型

    IgG
  • 应用备注

    Western Blot: use at 1-5 μg/mL.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS

    注意事项

    Centrifuge vial prior to opening.

    储存条件

    4 °C,-20 °C

    储存方法

    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

    有效期

    24 months
  • 抗原

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    别名

    VEGFR-2/Flk-1

    背景

    Soluble vascular endothelial growth factor receptor-2 , soluble Kdr, soluble Ly73, soluble Flk-1, sVEGFR2, sVEGF receptor 2, soluble kinase insert domain protein receptor,The antibody recognizes solely the endogenous soluble form of mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. The endogenous soluble mouse esFlk-1 generated by alternative splicing consists of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle, other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C, ligand binding plays a key role in vascular development and vascular permeability.

    基因ID

    16542

    UniProt

    P35918

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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