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VEGFR2/CD309 抗体 (Soluble)

This anti-VEGFR2/CD309 antibody is a 兔 多克隆 antibody detecting VEGFR2/CD309 in WB. Suitable for 人.
产品编号 ABIN1589803
发货至: 中国

Quick Overview for VEGFR2/CD309 抗体 (Soluble) (ABIN1589803)

抗原

See all VEGFR2/CD309 (VEGFR2) 抗体
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

适用

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宿主

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克隆类型

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多克隆

标记

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This VEGFR2/CD309 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Soluble

    原理

    VEGFR-2/KDR (Peptide), soluble antibody

    特异性

    Peptide: CGRETILDHSAEAVGMP.

    产品特性

    Chromosomal location: 4q11-q12
    Produced from sera of rabbits immunised with a peptide of the C-terminal end of native human soluble VEGFR-2/KDR (CGRETILDHSAEAVGMP).

    纯化方法

    Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A.

    免疫原

    Peptide: CGRETILDHSAEAVGMP.

    亚型

    IgG
  • 应用备注

    Western Blot: Use 1-5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS

    注意事项

    Centrifuge vial prior to opening.

    储存条件

    4 °C,-20 °C

    储存方法

    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

    有效期

    24 months
  • 抗原

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    别名

    VEGFR-2/KDR

    背景

    Soluble vascular endothelial growth factor receptor-2 , soluble KDR, soluble FLK1, soluble CD309, VEGF receptor 2, sKDR,VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

    基因ID

    3791

    NCBI登录号

    NM_002253, NP_002244

    UniProt

    P35968

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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