PODXL 抗体
Quick Overview for PODXL 抗体 (ABIN1589722)
抗原
See all PODXL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Membrane protein fraction of isolated human glomeruli
-
产品特性
-
Chromosomal location: 7q32-q33
Monoclonal antibodies were produced with the help of BALB/c mice using a membrane protein fraction of isolated human glomeruli as the immunizing antigen. -
纯化方法
- The mouse IgG1 antibody (#4D5aE5E6) from hybridomas was purified from cell culture supernatant by Protein G chromatography.
-
亚型
- IgG1
-
-
-
-
应用备注
- IF/IHC: use at 2-5 µg/mL.
-
说明
-
Monoclonal Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
-
缓冲液
- PBS
-
注意事项
- Centrifuge vial prior to opening.
-
储存条件
- -20 °C
-
储存方法
- The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
-
有效期
- 6 months
-
-
- PODXL (Podocalyxin-Like (PODXL))
-
别名
- Podocalyxin
-
背景
-
Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes. It was shown that endothelial cell membranes contain Podocalyxin. By immunoelectron microscopy Podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of Podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. It is concluded that (a) Podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface.
Synonyms: PODXL, PC, PCLP, Gp200, PCLP-1, Podocalyxin-like protein, GCTM-2 antigen, Gp200 -
NCBI登录号
- NM_001018111, NP_001018121
-
UniProt
- O00592
-
途径
- Tube Formation
抗原
-