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PODXL 抗体

This anti-PODXL antibody is a 小鼠 单克隆 antibody detecting PODXL in IF 和 IHC (p). Suitable for 人.
产品编号 ABIN1589722
发货至: 中国

Quick Overview for PODXL 抗体 (ABIN1589722)

抗原

See all PODXL 抗体
PODXL (Podocalyxin-Like (PODXL))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PODXL antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

GB6D9
  • 特异性

    Membrane protein fraction of isolated human glomeruli

    产品特性

    Chromosomal location: 7q32-q33
    Monoclonal antibodies were produced with the help of BALB/c mice using a membrane protein fraction of isolated human glomeruli as the immunizing antigen.

    纯化方法

    The mouse IgG1 antibody (#4D5aE5E6) from hybridomas was purified from cell culture supernatant by Protein G chromatography.

    亚型

    IgG1
  • 应用备注

    IF/IHC: use at 2-5 µg/mL.

    说明

    Monoclonal Antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS

    注意事项

    Centrifuge vial prior to opening.

    储存条件

    -20 °C

    储存方法

    The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

    有效期

    6 months
  • 抗原

    PODXL (Podocalyxin-Like (PODXL))

    别名

    Podocalyxin

    背景

    Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes. It was shown that endothelial cell membranes contain Podocalyxin. By immunoelectron microscopy Podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of Podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. It is concluded that (a) Podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface.
    Synonyms: PODXL, PC, PCLP, Gp200, PCLP-1, Podocalyxin-like protein, GCTM-2 antigen, Gp200

    NCBI登录号

    NM_001018111, NP_001018121

    UniProt

    O00592

    途径

    Tube Formation
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