TEK 抗体 (Biotin)
Our Local Distributor
北京 101111
Quick Overview for TEK 抗体 (Biotin) (ABIN155165)
抗原
See all TEK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The unconjugated monoclonal antibody will detect native human TIE-2 /TEK in ELISA experiments and on the surface of different human cell types.
-
纯化方法
- Protein G purified
-
免疫原
- Recombinant human soluble CD202b / TIE-2 protein
-
亚型
- IgG1
-
-
-
-
应用备注
-
Western Blot. ELISA. FACS analysis and cell sorting: 2 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
溶解方式
- Restore to a concentration of 0.1-1.0 mg/mL with sterile water. Centrifuge vial prior to opening
-
缓冲液
- PBS, 50x BSA, 0.02 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for two weeks or (in aliquots) at -20 °C for longer.
-
-
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
-
别名
- CD202b / TEK
-
背景
- TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
-
基因ID
- 7010
-
NCBI登录号
- NP_000450
-
UniProt
- Q02763
-
途径
- RTK signaling, Growth Factor Binding
抗原
-