BRCA1 抗体
Our Local Distributor
北京 101111
Quick Overview for BRCA1 抗体 (ABIN155101)
抗原
See all BRCA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects BRCA1.
-
纯化方法
- Affinity Chromatography
-
免疫原
- Synthetic peptide surrounding amino acid 1852 of Human BRCA1
-
-
anti-Breast Cancer 1 (BRCA1) (AA 120-220) antibody
BRCA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 19-83) antibodyBRCA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 229-335) antibodyBRCA1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 6C6D2 unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 1661-1863) antibodyBRCA1 适用: 人, 大鼠, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 445-620) antibodyBRCA1 适用: 人 IHC 宿主: 小鼠 Monoclonal BRCA1-1398 unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 525-575) antibodyBRCA1 适用: 小鼠 WB, IP 宿主: 兔 Monoclonal BLR319M unconjugated Recombinant Antibody
anti-Breast Cancer 1 (BRCA1) (Ser184), (Ser186) antibodyBRCA1 适用: 人, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 1681-1781) antibodyBRCA1 适用: 人, 大鼠, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 1314-1600), (AA 1314-1864) antibodyBRCA1 适用: 人 WB, IF, IP, FACS, ICC 宿主: 小鼠 Monoclonal RAY unconjugated
anti-Breast Cancer 1 (BRCA1) (AA 64-160) antibodyBRCA1 适用: 大鼠, 小鼠 ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western Blot: 1-4 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.2 mg/mL
-
缓冲液
- PBS, pH 7.2 containing 30 % Glycerol, 0.01 % Thimerosal, 0.5 % BSA
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C/-80 °C
-
储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
-
-
- BRCA1 (Breast Cancer 1 (BRCA1))
-
别名
- BRCA1 / RNF53
-
背景
- BRCA1 is a breast cancer susceptibility gene that was localized to chromosome 17q. Mutations within this gene are believed to account for approximately 45 % of families with high incidence of breast cancer and at least 80 % of families with increased incidence of both earlyonset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. Like many other genes involved in familial cancer, BRCA1 appears to encode a tumor suppressor, a protein that acts as a negative regulator of tumor growth.Synonyms: Breast cancer type 1 susceptibility protein, RING finger protein 53
-
基因ID
- 672
-
NCBI登录号
- NP_009225
-
UniProt
- P38398
-
途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
抗原
-
