BIRC7 抗体 (C-Term)
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Quick Overview for BIRC7 抗体 (C-Term) (ABIN155074)
抗原
See all BIRC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- The antibody detects a band at ~33 kDa and a weaker band at 30 kDa, corresponding to Livin α and β.
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纯化方法
- Peptide affinity purified
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免疫原
- Synthetic peptide surrounding amino acid near the C- terminus of the long form of human Livin
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应用备注
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Western Blot: 2-6 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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别名
- BIRC7 / LIVIN
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背景
- Livin is a novel member in the IAP (inhibitor of apoptosis) protein family. Livin contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin-α and Livin-β. Transfection of Livin protected cells from apoptosis induced by FADD, BAX, RIP, RIP3 and DR6. Livin directly react with several caspases including Caspase-3, -7, and -9, and it inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c and ATP.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50
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基因ID
- 79444
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NCBI登录号
- NP_071444
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UniProt
- Q96CA5
抗原
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