FASL 抗体
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北京 101111
Quick Overview for FASL 抗体 (ABIN155064)
抗原
See all FASL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects Fas Ligand.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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产品特性
- Synonyms: FASLG, APT1LG1, FASL, TNFSF6, CD95L protein, APTL, Tumor necrosis factor ligandsuperfamily member 6, Fas antigen ligand, Apoptosis antigen ligand
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纯化方法
- Affiniry Chromatography on Protein G
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免疫原
- Recombinant Human Fas Ligand.
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亚型
- IgG1
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应用备注
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Western Blot (1-4 μg/mL): HeLa cell lysate can be used as a Positive Control and a 40 kDaband should be detected. Immunoprecipitation. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2, 0.02 % Thimerosal, 50 % Glycerol, 1 % BSA
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C/-80 °C
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储存方法
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Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C -70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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别名
- CD178 / Fas Ligand
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背景
- Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when crosslinked with agonistic anti-Fas antibodies or Fas ligand (FasL). FasL is a tumor necrosis factor (TNF)-related type II membrane protein and is expressed in various tissue and cells. Both Fas and FasL are thought to play an important role in the apoptosis processes that takes place during T cell development.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
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基因ID
- 356
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UniProt
- P48023
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途径
- Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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