PDK4 抗体
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北京 101111
Quick Overview for PDK4 抗体 (ABIN1539836)
抗原
See all PDK4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- Purified His-tagged PDK4 protein(Fragment) was used to produced this monoclonal antibody.
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亚型
- IgG1
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应用备注
- WB: 1:1000. WB: 1:500-1:1000. WB: 1:250
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- PDK4 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
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别名
- PDK4
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背景
- This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
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分子量
- 46469
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基因ID
- 5166
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NCBI登录号
- NP_002603
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UniProt
- Q16654
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途径
- PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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