我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

ABCB1 抗体 (AA 647-677)

Name: ABCB1 抗体 (AA 647-677)
SKU: ABIN1538560
Availability: OutOfStock

ABCB1 适用: 人 WB 宿主: 兔 Polyclonal RB2208 unconjugated

ABCB1 Antibody (ABIN1538560 and ABIN2840587) western blot analysis in K562 cell line lysates (35 μg/lane).

1 image

(2 references)

产品编号 ABIN1538560

发货至: 中国

Datasheet as PDF

抗原 See all ABCB1 抗体

ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
抗原表位
6

5

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 647-677
适用
67

16

12

5

5

3

2

2

1

1

1

1

1

1

1

1

1
人
宿主
46

25
兔
Compatible Secondaries
克隆类型
43

28
多克隆
标记
48

4

4

3

2

2

1

1

1

1

1

1

1

1
This ABCB1 antibody is un-conjugated
应用范围
37

24

23

19

15

13

10

9

3

2

1

1

1
Western Blotting (WB)

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This P-Glycoprotein (ABCB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the Central region of human P-Glycoprotein (ABCB1).

克隆位点

RB2208

亚型

Ig Fraction

Top Product

Discover our top product ABCB1 Primary Antibody
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 995-1280) antibody
ABCB1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C7 unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 995-1280) antibody
ABCB1 适用: 人 IHC, IHC (p) 宿主: 小鼠 Monoclonal 5B3 unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) antibody
ABCB1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 236-297) antibody
ABCB1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 1149-1280) antibody
ABCB1 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 4G6F4 unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 632-693) antibody
ABCB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6G11C12 unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 863-912) antibody
ABCB1 适用: 人, 小鼠, 大鼠, 兔, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 630-710) antibody
ABCB1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (Internal Region) antibody
ABCB1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (Middle Region) antibody
ABCB1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Pig, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

P-Glycoprotein (ABCB1) Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Kuo, Lee, Chen, Yang, Lin, Tsai, Wuputra, Lee, Ku, Miyoshi, Nakamura, Saito, Wu, Chai, Eckner, Steve Lin, Wang, Wu, Lin, Yokoyama: "Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 11, pp. 2613-2624, (2018) (PubMed).

Xiang, Zhang, Lu, Tang, Liang, Shi, Song, Gao: "A P-glycoprotein gene serves as a component of the protective mechanisms against 2-tridecanone and abamectin in Helicoverpa armigera." in: Gene, Vol. 627, pp. 63-71, (2017) (PubMed).
抗原

ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

别名

P-Glycoprotein (ABCB1) (ABCB1 产品)

别名

ABC20 antibody, CD243 antibody, CLCS antibody, GP170 antibody, MDR1 antibody, P-GP antibody, PGY1 antibody, Abcb1 antibody, Mdr1a antibody, p-gp antibody, xemdr antibody, Mdr1 antibody, Mdr1b antibody, Pgy-1 antibody, Pgy1 antibody, mdr antibody, ABCB1 antibody, PGP1 antibody, ATP binding cassette subfamily B member 1 antibody, ATP binding cassette subfamily B member 1A antibody, ATP binding cassette subfamily B member 1 L homeolog antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, ABCB1 antibody, Abcb1a antibody, abcb1.L antibody, Abcb1b antibody, Abcb1 antibody

背景

The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

分子量

141479

基因ID

5243

NCBI登录号

NP_000918

UniProt

P08183