TFE3 抗体 (C-Term)
Quick Overview for TFE3 抗体 (C-Term) (ABIN1537398)
抗原
See all TFE3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 489-516, C-Term
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预测反应
- B
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TFE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-516 amino acids from the C-terminal region of human TFE3.
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亚型
- Ig Fraction
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anti-Transcription Factor E3 (TFE3) (Internal Region) antibody
TFE3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor E3 (TFE3) antibodyTFE3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Transcription Factor E3 (TFE3) (AA 1-30), (N-Term) antibodyTFE3 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB20263 unconjugated
anti-Transcription Factor E3 (TFE3) (AA 1-110) antibodyTFE3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor E3 (TFE3) (AA 1-575) antibodyTFE3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor E3 (TFE3) (AA 1-30) antibodyTFE3 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor E3 (TFE3) (AA 166-254) antibodyTFE3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transcription Factor E3 (TFE3) (N-Term) antibodyVerified TFE3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Transcription Factor E3 (TFE3) (AA 324-373) antibodyTFE3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Pig, 斑马鱼, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor E3 (TFE3) (AA 503-552) antibodyTFE3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- TFE3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- TFE3 (Transcription Factor E3 (TFE3))
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别名
- TFE3
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背景
- The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF, TFE3, TFEB and TFEC. The TEF3 protein encoded by this gene activates transcription through binding to the muE3 motif of the immunoglobulin heavy-chain enhancer. The TFEC protein forms heterodimers with the TEF3 protein and inhibits TFE3-dependent transcription activation. The TEF3 protein interacts with transcription regulators such as E2F3, SMAD3, and LEF-1, and is involved in TGF-beta-induced transcription, playing important roles in cell growth, proliferation, and osteoclast and macrophage differentiation. The TFE3 protein also activates hepatic IRS-2 gene, and induces hexokinase II (HK2) and insulin-induced gene 1 (INSIG1), it participates in insulin signaling and could be a therapeutic target for diabetes. This gene is also involved in chromosomal translocations, resulting in different fusion gene products in papillary renal cell carcinomas and alveolar soft part sarcomas, such as PRCC-TFE3, RCC17-TFE3, PSF-TFE3, NonO (p54nrb)-TFE3 and ASPL-TFE3.
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分子量
- 61521
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基因ID
- 7030
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NCBI登录号
- NP_006512
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UniProt
- P19532
抗原
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