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CD40 抗体 (C-Term)

Name: CD40 抗体 (C-Term)
SKU: ABIN1536939
Availability: OutOfStock

CD40 适用: 人 WB 宿主: 兔 Polyclonal RB21158 unconjugated

Western blot analysis of lysate from human spleen tissue lysate, using CD40 Antibody (C-term) B. (CD40 抗体 (C-Term))

1 image

产品编号 ABIN1536939

发货至: 中国

Datasheet as PDF

抗原 See all CD40 抗体

CD40
抗原表位
18

17

16

14

14

9

8

5

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 247-276, C-Term
适用
181

103

19

19

8

6

6

5

4

3

2

2

2

2

1
人
宿主
106

94

47

5

4

1
兔
Compatible Secondaries
克隆类型
166

82

7
多克隆
标记
129

23

23

15

11

5

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD40 antibody is un-conjugated
应用范围
161

86

62

50

36

28

24

20

17

14

13

12

5

5

4

4

4

4

4

3

3

3

2

2

2

1

1
Western Blotting (WB)

预测反应

M

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This CD40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the C-terminal region of human CD40.

克隆位点

RB21158

亚型

Ig Fraction

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anti-CD40 (CD40) (C-Term) antibody
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anti-CD40 (CD40) (AA 21-193) antibody
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anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 适用: 人 FACS, IHC, St 宿主: 小鼠 Monoclonal 5C3 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD40 (CD40) antibody
CD40 适用: 人 FACS, IHC, IP, Act 宿主: 兔 Chimeric G28-5 unconjugated Recombinant Antibody

anti-CD40 (CD40) antibody
CD40 适用: 人 FACS 宿主: 小鼠 Monoclonal HI40a unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 适用: 人 FACS 宿主: 小鼠 Monoclonal HI40a FITC

应用备注

WB: 1:1000. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

CD40 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

有效期

6 months
抗原

CD40

别名

CD40 (CD40 产品)

背景

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

分子量

30619

基因ID

958

NCBI登录号

NP_001241, NP_690593

UniProt

P25942

途径

NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints