CASC5 抗体 (C-Term)
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Quick Overview for CASC5 抗体 (C-Term) (ABIN1536748)
抗原
See all CASC5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1557-1583, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Casc5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Mouse Casc5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- CASC5 (Cancer Susceptibility Candidate 5 (CASC5))
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别名
- Casc5
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背景
- Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).
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基因ID
- 76464
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UniProt
- Q66JQ7
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途径
- Maintenance of Protein Location, Autophagy
抗原
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