Actin 抗体
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- 抗原 See all Actin (ACTA1) 抗体
- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Actin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 预测反应
- B, C, M, Pig, Rb, Rat
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This ACTA1 monoclonal antibody is generated from mouse immunized with ACTA1 recombinant protein.
- 克隆位点
- 337CT30-10-1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ACTA1 Primary Antibody
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- 应用备注
- WB: 1:500-1:1000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- ACTA1 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding." in: Journal of cell science, Vol. 129, Issue 6, pp. 1115-27, (2017) (PubMed).
: "PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells." in: Molecular biology of the cell, Vol. 28, Issue 10, pp. 1389-1399, (2017) (PubMed).
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Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding." in: Journal of cell science, Vol. 129, Issue 6, pp. 1115-27, (2017) (PubMed).
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- 抗原
- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
- 别名
- ACTA1 (ACTA1 产品)
- 背景
- The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
- 分子量
- 42051
- 基因ID
- 58
- NCBI登录号
- NP_001091
- UniProt
- P68133
- 途径
- Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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