NOTCH2 抗体 (Cleaved-Val1697)
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北京 101111
Quick Overview for NOTCH2 抗体 (Cleaved-Val1697) (ABIN1536150)
抗原
See all NOTCH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1678-1727, Cleaved-Val1697
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原理
- Cleaved-Notch 2 (V1697) Antibody
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特异性
- Cleaved-Notch 2 (V1697) Polyclonal Antibody detects endogenous levels of fragment of activated Notch 2 protein resulting from cleavage adjacent to V1697.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human NOTCH2. AA range:1678-1727
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NOTCH2 (Notch 2 (NOTCH2))
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别名
- NOTCH2
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背景
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Synonyms: NOTCH2, Neurogenic locus notch homolog protein 2, Notch 2, hN2
Background: notch 2(NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle
Gene Name: NOTCH2
Protein Name: Neurogenic locus notch homolog protein 2
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分子量
- 83 kDa
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基因ID
- 4853
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OMIM
- 600275
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UniProt
- Q04721
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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