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NOTCH2 抗体 (Cleaved-Val1697)

This 兔 多克隆 antibody specifically detects NOTCH2 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1536150
发货至: 中国
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Quick Overview for NOTCH2 抗体 (Cleaved-Val1697) (ABIN1536150)

抗原

See all NOTCH2 抗体
NOTCH2 (Notch 2 (NOTCH2))

适用

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  • 28
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  • 2
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  • 1
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人, 小鼠, 大鼠

宿主

  • 94
  • 9
  • 7
  • 5
  • 2
  • 1
兔

克隆类型

  • 91
  • 24
  • 2
多克隆

标记

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  • 5
  • 5
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This NOTCH2 antibody is un-conjugated

应用范围

  • 65
  • 43
  • 32
  • 31
  • 28
  • 28
  • 14
  • 12
  • 7
  • 7
  • 2
  • 2
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Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 15
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    • 5
    • 5
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    • 2
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    AA 1678-1727, Cleaved-Val1697

    原理

    Cleaved-Notch 2 (V1697) Antibody

    特异性

    Cleaved-Notch 2 (V1697) Polyclonal Antibody detects endogenous levels of fragment of activated Notch 2 protein resulting from cleavage adjacent to V1697.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human NOTCH2. AA range:1678-1727

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    NOTCH2 (Notch 2 (NOTCH2))

    别名

    NOTCH2

    背景

    Synonyms: NOTCH2, Neurogenic locus notch homolog protein 2, Notch 2, hN2

    Background: notch 2(NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle

    Gene Name: NOTCH2

    Protein Name: Neurogenic locus notch homolog protein 2

    分子量

    83 kDa

    基因ID

    4853

    OMIM

    600275

    UniProt

    Q04721

    途径

    Notch Signaling, Stem Cell Maintenance
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