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ITGA5 抗体 (Cleaved-Glu895)

The 兔 多克隆 anti-ITGA5 antibody is suitable to detect ITGA5 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN1536133
发货至: 中国
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Quick Overview for ITGA5 抗体 (Cleaved-Glu895) (ABIN1536133)

抗原

See all ITGA5 抗体
ITGA5 (Integrin, alpha 5 (ITGA5))

适用

  • 147
  • 90
  • 56
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 127
  • 18
  • 12
  • 6
  • 4
兔

克隆类型

  • 102
  • 66
多克隆

标记

  • 74
  • 15
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  • 5
  • 3
  • 3
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  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This ITGA5 antibody is un-conjugated

应用范围

  • 97
  • 69
  • 49
  • 42
  • 21
  • 21
  • 17
  • 15
  • 14
  • 14
  • 9
  • 3
  • 1
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  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 12
    • 12
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 876-925, Cleaved-Glu895

    原理

    Cleaved-Integrin α5 LC (E895) Antibody

    特异性

    Cleaved-Integrin α5 LC (E895) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α5 LC protein resulting from cleavage adjacent to E895.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human ITGA5. AA range:876-925

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    ITGA5 (Integrin, alpha 5 (ITGA5))

    别名

    ITGA5

    背景

    Synonyms: ITGA5, FNRA, Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD antigen CD49e

    Background: integrin subunit alpha 5(ITGA5) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],

    Gene Name: ITGA5

    Protein Name: Integrin alpha-5

    分子量

    18 kDa

    基因ID

    3678

    OMIM

    135620

    UniProt

    P08648

    途径

    Integrin Complex
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