ITGA5 抗体 (Cleaved-Glu895)
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Quick Overview for ITGA5 抗体 (Cleaved-Glu895) (ABIN1536133)
抗原
See all ITGA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 876-925, Cleaved-Glu895
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原理
- Cleaved-Integrin α5 LC (E895) Antibody
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特异性
- Cleaved-Integrin α5 LC (E895) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α5 LC protein resulting from cleavage adjacent to E895.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ITGA5. AA range:876-925
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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别名
- ITGA5
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背景
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Synonyms: ITGA5, FNRA, Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD antigen CD49e
Background: integrin subunit alpha 5(ITGA5) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],
Gene Name: ITGA5
Protein Name: Integrin alpha-5
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分子量
- 18 kDa
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基因ID
- 3678
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OMIM
- 135620
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UniProt
- P08648
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途径
- Integrin Complex
抗原
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