Notch1 抗体 (Cleaved-Val1754)
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Quick Overview for Notch1 抗体 (Cleaved-Val1754) (ABIN1536094)
抗原
See all Notch1 (NOTCH1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1735-1784, Cleaved-Val1754
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原理
- Cleaved-Notch 1 (V1754) Antibody
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特异性
- Cleaved-Notch 1 (V1754) Polyclonal Antibody detects endogenous levels of fragment of activated Notch 1 protein resulting from cleavage adjacent to V1754.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Notch 1. AA range:1735-1784
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亚型
- IgG
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anti-Notch 1 (NOTCH1) antibody (APC)
NOTCH1 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal mN1A APC
anti-Notch 1 (NOTCH1) antibody (PE)NOTCH1 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal mN1A PE
anti-Notch 1 (NOTCH1) (AA 1919-2079) antibodyNOTCH1 适用: 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 1 (NOTCH1) (AA 2101-2300) antibodyNOTCH1 适用: 人 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (Atto 390)NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 Atto 390
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (Atto 488)NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 Atto 488
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (Atto 594)NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 Atto 594
anti-Notch 1 (NOTCH1) (AA 20-216) antibodyNOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 unconjugated
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (APC)NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 APC
anti-Notch 1 (NOTCH1) (AA 20-216) antibody (Biotin)NOTCH1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S253-32 Biotin
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应用备注
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
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别名
- Notch 1
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背景
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Synonyms: NOTCH1, TAN1, Neurogenic locus notch homolog protein 1, Notch 1, hN1, Translocation-associated notch protein TAN-1
Background: notch 1(NOTCH1) Homo sapiens This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymph
Gene Name: NOTCH1
Protein Name: Neurogenic locus notch homolog protein 1
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分子量
- 110 kDa
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基因ID
- 4851
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OMIM
- 190198
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UniProt
- P46531
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途径
- Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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