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RENT1/UPF1 抗体 (AA 299-348)

The 兔 多克隆 anti-RENT1/UPF1 antibody is suitable to detect RENT1/UPF1 in samples from 人 和 小鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1535287
发货至: 中国
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Quick Overview for RENT1/UPF1 抗体 (AA 299-348) (ABIN1535287)

抗原

See all RENT1/UPF1 (UPF1) 抗体
RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

适用

  • 95
  • 48
  • 31
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 73
  • 21
  • 3
兔

克隆类型

  • 62
  • 35
多克隆

标记

  • 44
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RENT1/UPF1 antibody is un-conjugated

应用范围

  • 62
  • 44
  • 40
  • 31
  • 29
  • 26
  • 19
  • 14
  • 13
  • 8
  • 3
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 25
    • 15
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 299-348

    原理

    Rent1 Antibody

    特异性

    Rent1 Polyclonal Antibody detects endogenous levels of Rent1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human UPF1. AA range:299-348

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

    别名

    UPF1

    背景

    Synonyms: UPF1, KIAA0221, RENT1, Regulator of nonsense transcripts 1, ATP-dependent helicase RENT1, Nonsense mRNA reducing factor 1, NORF1, Up-frameshift suppressor 1 homolog, hUpf1

    Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

    Gene Name: UPF1

    Protein Name: Regulator of nonsense transcripts 1

    分子量

    124 kDa

    基因ID

    5976

    OMIM

    601430

    UniProt

    Q92900

    途径

    SARS-CoV-2 Protein Interactome
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