PDK2 抗体 (AA 260-309)
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Quick Overview for PDK2 抗体 (AA 260-309) (ABIN1535242)
抗原
See all PDK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 260-309
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原理
- PDK2 Antibody
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特异性
- PDK2 Polyclonal Antibody detects endogenous levels of PDK2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PDK2. AA range:260-309
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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别名
- PDK2
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背景
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Synonyms: PDK2, PDHK2, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial, Pyruvate dehydrogenase kinase isoform 2
Background: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
Gene Name: PDK2
Protein Name: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2 mitochondrial
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分子量
- 46 kDa
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基因ID
- 5164
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OMIM
- 602525
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UniProt
- Q15119
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途径
- PI3K-Akt Signaling, RTK signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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