Fibulin 5 抗体 (AA 171-220)
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Quick Overview for Fibulin 5 抗体 (AA 171-220) (ABIN1534905)
抗原
See all Fibulin 5 (FBLN5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 171-220
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原理
- Fibulin-5 Antibody
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特异性
- Fibulin-5 Polyclonal Antibody detects endogenous levels of Fibulin-5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FBLN5. AA range:171-220
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Fibulin 5 (FBLN5)
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别名
- FBLN5
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背景
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Synonyms: FBLN5, DANCE, Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50
Background: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore,The protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008],
Gene Name: FBLN5
Protein Name: Fibulin-5
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分子量
- 50 kDa
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基因ID
- 10516
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OMIM
- 604580
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UniProt
- Q9UBX5
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途径
- SARS-CoV-2 Protein Interactome
抗原
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