MUTYH 抗体 (AA 151-200)
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北京 101111
Quick Overview for MUTYH 抗体 (AA 151-200) (ABIN1534474)
抗原
See all MUTYH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-200
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原理
- MYH Antibody
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特异性
- MYH Polyclonal Antibody detects endogenous levels of MYH protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MUTYH. AA range:151-200
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MUTYH (MutY Homolog (E. Coli) (MUTYH))
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别名
- MUTYH
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背景
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Synonyms: MUTYH, MYH, A/G-specific adenine DNA glycosylase, MutY homolog, hMYH
Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: MUTYH
Protein Name: A/G-specific adenine DNA glycosylase
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分子量
- 60 kDa
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基因ID
- 4595
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OMIM
- 137215
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UniProt
- Q9UIF7
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途径
- DNA Damage Repair
抗原
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