MSH2 抗体 (AA 541-590)
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北京 101111
Quick Overview for MSH2 抗体 (AA 541-590) (ABIN1534471)
抗原
See all MSH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 541-590
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原理
- MSH2 Antibody
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特异性
- MSH2 Polyclonal Antibody detects endogenous levels of MSH2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MSH2 (Mismatch Repair Protein 2 (MSH2))
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别名
- MSH2
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背景
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Synonyms: MSH2, DNA mismatch repair protein Msh2, hMSH2, MutS protein homolog 2
Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
Gene Name: MSH2
Protein Name: DNA mismatch repair protein Msh2
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分子量
- 104 kDa
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基因ID
- 4436
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OMIM
- 120435
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UniProt
- P43246
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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