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FGF23 抗体 (AA 151-200)

There is 1 publication for this product available. The 兔 多克隆 anti-FGF23 antibody is suitable to detect FGF23 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA 和 IF.
产品编号 ABIN1534408
发货至: 中国
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Quick Overview for FGF23 抗体 (AA 151-200) (ABIN1534408)

抗原

See all FGF23 抗体
FGF23 (Fibroblast Growth Factor 23 (FGF23))

适用

人, 大鼠, 小鼠

宿主

  • 113
  • 78
  • 2
兔

克隆类型

  • 111
  • 82
多克隆

标记

  • 132
  • 12
  • 9
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This FGF23 antibody is un-conjugated

应用范围

  • 78
  • 66
  • 46
  • 45
  • 10
  • 7
  • 6
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 45
    • 38
    • 12
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-200

    原理

    FGF-23 Antibody

    特异性

    FGF-23 Polyclonal Antibody detects endogenous levels of FGF-23 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FGF23. AA range:151-200

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • Sun, Zou, Yang, Morita, Gong, Shiba, Akagawa, Yuan: "Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway." in: Biochemical and biophysical research communications, Vol. 428, Issue 2, pp. 298-302, (2012) (PubMed).

  • 抗原

    FGF23 (Fibroblast Growth Factor 23 (FGF23))

    别名

    FGF23

    背景

    Synonyms: FGF23, HYPF, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor

    Background: This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013],

    Gene Name: FGF23

    Protein Name: Fibroblast growth factor 23

    分子量

    27 kDa

    基因ID

    8074

    OMIM

    193100

    UniProt

    Q9GZV9

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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