FGF23 抗体 (AA 151-200)
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北京 101111
Quick Overview for FGF23 抗体 (AA 151-200) (ABIN1534408)
抗原
See all FGF23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 151-200
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原理
- FGF-23 Antibody
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特异性
- FGF-23 Polyclonal Antibody detects endogenous levels of FGF-23 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FGF23. AA range:151-200
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway." in: Biochemical and biophysical research communications, Vol. 428, Issue 2, pp. 298-302, (2012) (PubMed).
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- FGF23 (Fibroblast Growth Factor 23 (FGF23))
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别名
- FGF23
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背景
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Synonyms: FGF23, HYPF, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor
Background: This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013],
Gene Name: FGF23
Protein Name: Fibroblast growth factor 23
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分子量
- 27 kDa
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基因ID
- 8074
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OMIM
- 193100
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UniProt
- Q9GZV9
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
抗原
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