ADRB1 抗体 (AA 281-330)
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Quick Overview for ADRB1 抗体 (AA 281-330) (ABIN1534260)
抗原
See all ADRB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 281-330
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原理
- AR-β1 Antibody
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特异性
- AR-β1 Polyclonal Antibody detects endogenous levels of AR-β1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ADRB1. AA range:281-330
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
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别名
- ADRB1
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背景
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Synonyms: ADRB1, ADRB1R, B1AR, Beta-1 adrenergic receptor, Beta-1 adrenoreceptor, Beta-1 adrenoceptor
Background: The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008],
Gene Name: ADRB1
Protein Name: Beta-1 adrenergic receptor
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分子量
- 51 kDa
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基因ID
- 153
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OMIM
- 109630
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UniProt
- P08588
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途径
- cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation
抗原
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