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TP53I3 抗体 (AA 241-290)

The 兔 多克隆 anti-TP53I3 antibody (ABIN1533944) specifically detects TP53I3 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN1533944
发货至: 中国
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Quick Overview for TP53I3 抗体 (AA 241-290) (ABIN1533944)

抗原

See all TP53I3 抗体
TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

适用

  • 46
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 38
  • 8
兔

克隆类型

  • 40
  • 6
多克隆

标记

  • 24
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This TP53I3 antibody is un-conjugated

应用范围

  • 38
  • 24
  • 16
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 18
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 241-290

    原理

    PIG3 Antibody

    特异性

    PIG3 Polyclonal Antibody detects endogenous levels of PIG3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human QORX. AA range:241-290

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

    背景

    Synonyms: TP53I3, PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein

    Background: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Gene Name: TP53I3

    Protein Name: Quinone oxidoreductase PIG3

    分子量

    35 kDa

    基因ID

    9540

    OMIM

    605171

    UniProt

    Q53FA7

    途径

    p53 Pathway
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