TCF7 抗体 (AA 10-59)
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Quick Overview for TCF7 抗体 (AA 10-59) (ABIN1533714)
抗原
See all TCF7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-59
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原理
- TCF-1 Antibody
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特异性
- TCF-1 Polyclonal Antibody detects endogenous levels of TCF-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TCF7. AA range:10-59
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亚型
- IgG
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anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) antibody
TCF7 适用: 人 WB, IHC, IP, CUT&RUN 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 200-250) antibodyTCF7 适用: 人, 小鼠 WB, IHC, ICC 宿主: 兔 Monoclonal BLR228K unconjugated Recombinant Antibody
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 287-384) antibodyTCF7 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 287-384) antibodyTCF7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (AA 228-277) antibodyTCF7 适用: 人, Cow, 豚鼠, 马, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) antibodyTCF7 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) antibodyTCF7 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7) (N-Term) antibodyTCF7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))
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别名
- TCF7
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背景
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Synonyms: TCF7, TCF1, Transcription factor 7, TCF-7, T-cell-specific transcription factor 1, T-cell factor 1, TCF-1
Background: alternative products:2 series of isoforms, L and S, are produced by use of alternative promoter usage. Additional isoforms seem to exist,function:Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.,induction:By TCF7L2 and CTNNB1.,sequence caution:Wrong choice of frame.,similarity:Belongs to the TCF/LEF family.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the armadillo repeat of CTNNB1 and forms a stable complex. Interacts with AES, TLE1, TLE2, TLE3 and TLE4.,tissue specificity:Predominantly in T-cells. Also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium.,
Gene Name: TCF7
Protein Name: Transcription factor 7
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分子量
- 41 kDa
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基因ID
- 6932
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OMIM
- 189908
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UniProt
- P36402
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途径
- WNT signaling
抗原
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