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SKIL 抗体 (AA 616-665)

This 兔 多克隆 antibody specifically detects SKIL in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1533612
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SKIL 抗体 (AA 616-665) (ABIN1533612)

抗原

See all SKIL 抗体
SKIL (SKI-Like Oncogene (SKIL))

适用

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人, 小鼠

宿主

  • 67
  • 5
兔

克隆类型

  • 68
  • 4
多克隆

标记

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This SKIL antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 616-665

    原理

    SnoN Antibody

    特异性

    SnoN Polyclonal Antibody detects endogenous levels of SnoN protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human SKIL. AA range:616-665

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SKIL (SKI-Like Oncogene (SKIL))

    别名

    SKIL

    背景

    Synonyms: SKIL, SNO, Ski-like protein, Ski-related oncogene, Ski-related protein

    Background: The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

    Gene Name: SKIL

    Protein Name: Ski-like protein

    分子量

    77 kDa

    基因ID

    6498

    OMIM

    165340

    UniProt

    P12757

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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