SKIL 抗体 (AA 616-665)
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北京 101111
Quick Overview for SKIL 抗体 (AA 616-665) (ABIN1533612)
抗原
See all SKIL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 616-665
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原理
- SnoN Antibody
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特异性
- SnoN Polyclonal Antibody detects endogenous levels of SnoN protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human SKIL. AA range:616-665
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SKIL (SKI-Like Oncogene (SKIL))
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别名
- SKIL
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背景
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Synonyms: SKIL, SNO, Ski-like protein, Ski-related oncogene, Ski-related protein
Background: The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Gene Name: SKIL
Protein Name: Ski-like protein
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分子量
- 77 kDa
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基因ID
- 6498
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OMIM
- 165340
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UniProt
- P12757
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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