TRADD 抗体 (AA 251-300)
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Quick Overview for TRADD 抗体 (AA 251-300) (ABIN1533447)
抗原
See all TRADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-300
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原理
- TRADD Antibody
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特异性
- TRADD Polyclonal Antibody detects endogenous levels of TRADD protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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别名
- TRADD
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背景
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Synonyms: TRADD, Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain
Background: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008],
Gene Name: TRADD
Protein Name: Tumor necrosis factor receptor type 1-associated DEATH domain protein
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分子量
- 34 kDa
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基因ID
- 8717
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OMIM
- 603500
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UniProt
- Q15628
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
抗原
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