NRF2 抗体 (AA 556-605)
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Quick Overview for NRF2 抗体 (AA 556-605) (ABIN1533359)
抗原
See all NRF2 (NFE2L2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 556-605
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原理
- Nrf2 Antibody
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特异性
- Nrf2 Polyclonal Antibody detects endogenous levels of Nrf2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Nrf2. AA range:556-605
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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别名
- Nrf2
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背景
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Synonyms: NFE2L2, NRF2, Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2
Background: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015],
Gene Name: NFE2L2
Protein Name: Nuclear factor erythroid 2-related factor 2
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分子量
- 67 kDa
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基因ID
- 4780
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OMIM
- 600492
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UniProt
- Q16236
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途径
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
抗原
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