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NRF2 抗体 (AA 556-605)

This 兔 多克隆 antibody specifically detects NRF2 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1533359
发货至: 中国
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Quick Overview for NRF2 抗体 (AA 556-605) (ABIN1533359)

抗原

See all NRF2 (NFE2L2) 抗体
NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

适用

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人, 小鼠, 大鼠

宿主

  • 151
  • 15
  • 1
兔

克隆类型

  • 112
  • 55
多克隆

标记

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This NRF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 40
    • 15
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    • 1
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    • 1
    AA 556-605

    原理

    Nrf2 Antibody

    特异性

    Nrf2 Polyclonal Antibody detects endogenous levels of Nrf2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Nrf2. AA range:556-605

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

    别名

    Nrf2

    背景

    Synonyms: NFE2L2, NRF2, Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2

    Background: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters, many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015],

    Gene Name: NFE2L2

    Protein Name: Nuclear factor erythroid 2-related factor 2

    分子量

    67 kDa

    基因ID

    4780

    OMIM

    600492

    UniProt

    Q16236

    途径

    ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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