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FASL 抗体 (AA 101-150)

The 兔 多克隆 anti-FASL antibody (ABIN1533270) specifically detects FASL in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 Pig samples.
产品编号 ABIN1533270
发货至: 中国
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Quick Overview for FASL 抗体 (AA 101-150) (ABIN1533270)

抗原

See all FASL 抗体
FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

适用

  • 128
  • 21
  • 11
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
人, 小鼠, Pig

宿主

  • 86
  • 47
  • 5
  • 4
  • 2
  • 2
兔

克隆类型

  • 93
  • 53
多克隆

标记

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This FASL antibody is un-conjugated

应用范围

  • 86
  • 57
  • 29
  • 24
  • 17
  • 15
  • 14
  • 14
  • 14
  • 13
  • 6
  • 6
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  • 2
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 14
    • 9
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-150

    原理

    FAS-L Antibody

    特异性

    FAS-L Polyclonal Antibody detects endogenous levels of FAS-L protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FAS ligand. AA range:101-150

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

    别名

    FAS ligand

    背景

    Synonyms: FASLG, APT1LG1, CD95L, FASL, TNFSF6, Tumor necrosis factor ligand superfamily member 6, Apoptosis antigen ligand, APTL, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL, CD antigen CD178

    Background: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014],

    Gene Name: FASLG

    Protein Name: Tumor necrosis factor ligand superfamily member 6

    分子量

    31 kDa

    基因ID

    356

    OMIM

    134638

    UniProt

    P48023

    途径

    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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