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Cyclin A 抗体 (AA 221-270)

The 兔 多克隆 anti-Cyclin A antibody (ABIN1533247) specifically detects Cyclin A in WB, IHC, IF 和 ELISA. The antibody is reactive with 人, 小鼠, 大鼠 和 猴 samples.
产品编号 ABIN1533247
发货至: 中国
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Quick Overview for Cyclin A 抗体 (AA 221-270) (ABIN1533247)

抗原

See all Cyclin A (CCNA2) 抗体
Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

适用

  • 141
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  • 5
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人, 小鼠, 大鼠, 猴

宿主

  • 98
  • 46
  • 1
兔

克隆类型

  • 90
  • 55
多克隆

标记

  • 75
  • 8
  • 5
  • 5
  • 5
  • 5
  • 5
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  • 3
  • 3
  • 2
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  • 1
  • 1
  • 1
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  • 1
This Cyclin A antibody is un-conjugated

应用范围

  • 96
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  • 36
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  • 10
  • 3
  • 3
  • 3
  • 2
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 13
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    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-270

    原理

    Cyclin A Antibody

    特异性

    Cyclin A Polyclonal Antibody detects endogenous levels of Cyclin A protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Cyclin A. AA range:221-270

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

    别名

    Cyclin A

    背景

    Synonyms: CCNA1, Cyclin-A1, CCNA2, CCN1, CCNA, Cyclin-A2, Cyclin-A

    Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multi

    Gene Name: CCNA1/CCNA2

    Protein Name: Cyclin-A1/2

    分子量

    52 kDa

    基因ID

    8900, 890

    OMIM

    604036

    UniProt

    P78396

    途径

    PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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