Actin 抗体 (AA 1-50)
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北京 101111
Quick Overview for Actin 抗体 (AA 1-50) (ABIN1533206)
抗原
See all Actin (ACTA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Actin α1 Antibody
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特异性
- Actin α1 Polyclonal Antibody detects endogenous levels of Actin α1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Actin-alpha-1. AA range:1-50
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
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别名
- Actin-alpha-1
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背景
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Synonyms: ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1
Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008],
Gene Name: ACTA1
Protein Name: Actin alpha skeletal muscle
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分子量
- 42 kDa
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基因ID
- 58
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OMIM
- 102610
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UniProt
- P68133
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途径
- Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
抗原
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